Opioids block pain signals in the brain. When prescribed and used properly, opioids can help to make pain more manageable. Opioids also have dangerous side effects such as sleepiness, impaired thinking, addiction, overdose, and even death. Studies have shown that people who are prescribed opioids from multiple prescribers or obtain their opioid prescriptions from multiple pharmacies are more likely to overdose compared to those who receive their opioid prescriptions from only one prescriber.

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